Clinical Trial

The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial.

Study acronym: SNOWW

Withdrawn

View on ClinicalTrials.gov →

Why the trial stopped

Sponsor decided not to move forward with the site.

Summary

The primary objectives of this study are to determine if the inclusion of ctDNA testing in the evaluation and management of stages 2 and 3 rectal cancers will allow clinicians to improve their selection of patients for wait and watch (WW) management and to facilitate the detection of cancer regrowth during WW surveillance.

Protocol Amendment History 2 changes

critical Trial status changed: Not Yet Recruiting → Withdrawn 2026-06-10

notable Enrollment reduced: 200 -> 0 participants 2026-06-10

Trial Details

NCT Number	NCT07292285
Lead Sponsor	University of Colorado, Denver Collaborators: Natera, Inc.
Conditions	Cancer of the Rectum
Start Date	2026-10-01
Primary Completion	2029-12-31 (estimated)
Study Completion	2030-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-09