Restless Legs Syndrome in Temporomandibular Joint Disorders

This observational, cross-sectional, descriptive study aims to evaluate the prevalence of restless legs syndrome in patients with temporomandibular joint dysfunction and to investigate its effects on sleep quality and health-related quality of life. The study will be conducted in the otolaryngology outpatient clinic of Gaziantep City Hospital, Türkiye. Adults aged 18 to 65 years who are clinically diagnosed with temporomandibular joint dysfunction and meet the inclusion criteria will be invited to participate. An age- and sex-matched control group consisting of individuals without temporomandibular joint dysfunction will also be recruited. All participants will undergo face-to-face structured interviews during which standardized and validated questionnaires will be administered. The study will collect sociodemographic data, clinical characteristics, and responses to validated assessment tools measuring mandibular function, anxiety and depression symptoms, restless legs syndrome, sleep quality, and health-related quality of life.

NCT Number	NCT07292077
Lead Sponsor	Gulseren Demir Karakilic Collaborators: Bozok University, Gaziantep City Hospital
Conditions	Temporomandibular Joint Disorders, Restless Legs Syndrome, Sleep Quality
Enrollment	102 participants
Start Date	2025-02-20
Primary Completion	2025-06-30 (estimated)
Study Completion	2025-10-06 (estimated)
Updated on ClinicalTrials.gov	2025-12-29