High Dose Radiotherapy for Palliation (Hi-D)

Palliative radiation is effective for controlling or preventing symptoms such as pain, bleeding, dyspnea, and cord compression. Recently, studies have shown that additional dose escalation may result in superior local control. The investigators propose a phase II single arm trial to evaluate a novel high-dose radiation regimen, which will be 27 Gray in 3 fractions with dose escalation within the tumour (Hi-D).

NCT Number	NCT07291895
Lead Sponsor	British Columbia Cancer Agency
Conditions	Metastases, Palliative Radiotherapy
Enrollment	21 participants
Start Date	2027-03-01
Primary Completion	2030-07-01 (estimated)
Study Completion	2030-08-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-12