Clinical Trial

Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer

Recruiting Phase 2
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Summary
This is a single-center phase 2 study of to test how well the combination of toripalimab with chemotherapy followed by TORS or risk and response stratified de-escalated (chemo)radiotherapy works in patients with in HPV16+ locoregionally advanced oropharyngeal cancer (OPC).
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-12-16.
Status change: Not Yet Recruiting → Recruiting 2026-02-03
Trial Details
NCT Number NCT07290621
Lead Sponsor University of Chicago
Conditions Oropharyngeal Cancer
Enrollment 30 participants
Start Date 2026-02
Primary Completion 2030-02 (estimated)
Study Completion 2033-02 (estimated)
Updated on ClinicalTrials.gov 2026-02-06