Clinical Trial

Encouraging Older Adults and Adults With Serious Illness to Designate a Health Care Proxy

Enrolling by Invitation
View on ClinicalTrials.gov →
Summary
This study is a Stage III randomized trial to encourage patients in advance of a health care appointment to designate a healthcare proxy. Patients will be randomly assigned to receive a mailer containing information about designating a healthcare proxy, or to not receive any mailer. For patients assigned to receive a mailer, the mailer will differ by the presence or absence of a patient pre-commitment prompt, and contain a personalized provider request or a generic health system request. The work will evaluate the randomized trial and identify factors that predict intervention effectiveness.
Protocol Amendment History 9 changes
notable Enrollment reduced: 50000 -> 20000 participants 2026-08-04
critical Trial status changed: Not Yet Recruiting → Enrolling by Invitation 2026-06-16
notable Enrollment increased: 10000 -> 50000 participants 2026-06-16
notable Primary completion pushed: 2027-06-01 -> 2027-07-01 2026-06-16
minor Completion pushed: 2027-08-31 -> 2027-09-30 2026-06-16
notable Primary completion pushed: 2027-04-30 -> 2027-06-01 2026-04-14
minor Completion pushed: 2027-04-30 -> 2027-08-31 2026-04-14
notable Primary completion pushed: 2027-03-31 -> 2027-04-30 2026-04-02
minor Completion pushed: 2027-03-31 -> 2027-04-30 2026-04-02
Trial Details
NCT Number NCT07290478
Lead Sponsor University of Southern California
Collaborators: National Institute on Aging (NIA), Contra Costa Health
Conditions Designating a Healthcare Proxy
Enrollment 20,000 participants
Start Date 2026-06-01
Primary Completion 2027-07-15 (estimated)
Study Completion 2027-09-13 (estimated)
Updated on ClinicalTrials.gov 2026-08-03