Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth.

Researchers want to check how well garlic works inside permanent teeth as a medicament during root canal treatments. Garlic has shown to possess many helpful properties, like reducing inflammation, helping wounds heal, and antimicrobial characteristics. Because conventional medicaments can be expensive or have potential side effects, researchers are actively exploring natural options like garlic. Some lab studies have already shown that garlic gel can kill the microbes inside the teeth. However, no real-life clinical or X-ray studies have been done on using garlic in permanent teeth. This study may help scientists find a much safer and effective new material for dental treatments in the future.

NCT Number	NCT07289971
Lead Sponsor	University of Health Sciences Lahore
Conditions	Apical Periodontitis, Periapical Radiolucency
Enrollment	96 participants
Start Date	2026-01-20
Primary Completion	2026-03 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2026-01-06