Efficacy of Diacylglycerol Oil on Metabolic Risk Factors in Prediabetes

This study will implement a four-week dietary intervention among middle-aged and older adults with pre-diabetes. Participants assigned to the intervention arm will replace their usual cooking oil with diacylglycerol (DAG) oil, while those in the control arm will consume colza oil. All other lifestyle behaviors will be maintained without modification. The trial will determine the impact of DAG oil consumption on glycemic regulation, lipid metabolism, and body composition in this high-risk population.

NCT Number	NCT07289880
Lead Sponsor	The First Affiliated Hospital of Guangdong Pharmaceutical University
Conditions	Prediabetes
Enrollment	40 participants
Start Date	2025-12-30
Primary Completion	2026-12-01 (estimated)
Study Completion	2027-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-12-24