Glycemic Index of Date Cultivars and Date-based Products

Dates are widely consumed worldwide and hold substantial cultural importance in many Middle Eastern communities. Despite growing interest in measuring the glycemic response and glycemic index of foods for both research and practical applications, studies examining the glycemic properties of different date cultivars and their derived products remain limited. This study aims to determine the glycemic index (GI) and glycemic load (GL) of commonly consumed Saudi date cultivars and their derived products in healthy subjects, and to evaluate their potential impact on postprandial glucose responses. The study will consist of 4 phases as follows: phase 1: Date varieties at Tamer stage; phase 2: date varieties at Rutab stage; phase 3: Date's debs; phase 4: Date's paste. For each phase, ten subjects will be asked to attend the laboratory in the morning after an overnight fast on several occasions. Each visit will be separated from the next by a "washout" day. The reference food, 50 g of glucose dissolve in 250 ml water will be tested on 3 alternating days to diminish day to day variation of glucose tolerance. 50g equivalent carbohydrates of dates will be consumed with 250 ml of water. Participants will be blinded to the type of the dates. Glucose will be measured in capillary blood samples following the two hours of the test meal consumption, at 15 min interval (0, 15, 30, 45, 60, 90 and 120 min) . A qualified technician will perform all blood glucose measurements.

NCT Number	NCT07286981
Lead Sponsor	King Saud University
Conditions	Glycaemic Response Measurements
Enrollment	40 participants
Start Date	2024-08-16
Primary Completion	2025-05-25 (estimated)
Study Completion	2025-05-25 (estimated)
Updated on ClinicalTrials.gov	2025-12-31