Identifying Candidates for Limited Dissection at Microdissection TESE.

The goal of this retrospective observational study is to learn whether certain clinical characteristics can help predict which infertile men may successfully have sperm retrieved using a less-invasive "mini-incision" version of micro-TESE. The study focuses on men with very low or absent sperm counts (non-obstructive azoospermia, cryptozoospermia, or severe OAT). The main questions it aims to answer are: Can sperm be successfully found using only a small, limited-dissection micro-TESE in some men? Which clinical factors (such as hormone levels or medical history) help identify men who may benefit from this less-invasive approach? Researchers will compare men who had successful sperm retrieval with the mini-incision alone to men who required a more extensive micro-TESE to see if certain characteristics predict which approach is likely to work.

NCT Number	NCT07286279
Lead Sponsor	Clinique Ovo
Conditions	Non Obstructive Azoospermia, Cryptozoospermia, Oligoasthenoteratozoospermia, Male Infertility
Enrollment	248 participants
Start Date	2025-12-15
Primary Completion	2025-12-31 (estimated)
Study Completion	2026-01-15 (estimated)
Updated on ClinicalTrials.gov	2026-02-27