Virtual McKenzie Exercises and Centralization of Pain: A Pilot Study

Low back pain (LBP) is frequently managed in physical therapy using the McKenzie method, in which a patient's directional preference-most commonly extension-is used to guide treatment. Extension-based interventions are associated with symptom improvement and centralization in many individuals with LBP. At the same time, research in pain neuroscience has shown that people with LBP may have altered cortical representations of the low back, which may contribute to pain and disability. For patients who experience high pain levels or significant fear of movement, active directional preference exercises may be difficult to perform. Motor imagery, the mental simulation of movement without physical execution, has been shown to activate brain regions involved in movement and may help modify altered cortical representations. Preliminary research has suggested that virtual or imagery-based McKenzie extension exercises may improve pain and movement-related outcomes. This exploratory study aims to evaluate the immediate effects of a brief motor imagery-based extension protocol in adults with LBP who demonstrate a directional preference for extension. The study will assess changes in pain intensity, disability, fear-avoidance, pain catastrophization, lumbar flexion, straight leg raise, pain distribution, and symptom centralization following a single motor imagery session.

NCT Number	NCT07285824
Lead Sponsor	Evidence In Motion Collaborators: University of Nevada, Las Vegas, College of St. Scholastica, Inc.
Conditions	Chronic Pain, Low Back Pain
Enrollment	40 participants
Start Date	2025-12
Primary Completion	2026-05 (estimated)
Study Completion	2026-11 (estimated)
Updated on ClinicalTrials.gov	2025-12-16