Reducing Co-occurring Substance Use and HIV Risk Among Stimulant-using Men at High Risk for HIV in the United States of America.

This intervention will focus on stimulant-using men at high risk for HIV who are in need of tailored behavioral interventions to mitigate co-occurring stimulant use and HIV risk in the era of pre-exposure prophylaxis (PrEP). The study is a pilot randomized controlled trial to evaluate the adaptation, feasibility, acceptability, and preliminary efficacy of a behavioral intervention.

NCT Number	NCT07281378
Lead Sponsor	University of Florida Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Drug Use Disorders, PrEP Uptake, PrEP Adherence, HIV Risk Behavior
Enrollment	84 participants
Start Date	2026-07-20
Primary Completion	2027-05-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-30