Clinical Trial

Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness

Study acronym: APEX-Return
Recruiting
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Summary
The investigation is intended to evaluate the safety and effectiveness of the AlphaReturn Blood Management System when used in conjunction with the cleared AlphaVac MMA F1885 System for the treatment of acute pulmonary embolism.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-04-23
notable Primary completion pushed: 2026-11 -> 2026-12 2026-04-23
minor Completion pushed: 2026-11 -> 2026-12 2026-04-23
Trial Details
NCT Number NCT07280247
Lead Sponsor Angiodynamics, Inc.
Conditions Pulmonary Embolism Acute
Enrollment 39 participants
Start Date 2026-03-30
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-11