Study of Oral Food Challenge Biomarkers (SAFER)

This is a multi-center, mechanistic study. It is designed to learn more about signs in the body, called biomarkers, that might show if someone will have a reaction to peanut during a feeding test. The trial will enroll children ages 12 months to17 years old who are suspected of having an allergy to peanut. The primary objective is to identify a biomarker (or a combination of biomarkers) that will predict oral food challenge (OFC) (feeding test) results for participants with suspected peanut allergy.

NCT Number	NCT07279467
Lead Sponsor	National Institute of Allergy and Infectious Diseases (NIAID) Collaborators: Consortia for Food Allergy Research (CoFAR), Rho Federal Systems Division, Inc.
Conditions	Allergy
Enrollment	500 participants
Start Date	2026-04
Primary Completion	2027-10-01 (estimated)
Study Completion	2027-10-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-12