TVS, SHG, and MRI in Uterine Niche

Uterine niche is a defect formed by poor healing of the lower uterine myometrium after cesarean section, defined as a depression of at least 2mm in the uterine myometrium at the cesarean scar; it is associated with gynecological symptoms and even life-threatening pregnancy complications, so accurate imaging evaluation is crucial for diagnosis, symptom grading, and treatment planning. Currently, transvaginal ultrasound (TVS), saline hysterosonography (SHG), and magnetic resonance imaging (MRI) are commonly used for evaluation, but there are controversies about the consistency of their measurements and repeatability of results. This observational study, conducted at the International Peace Maternity and Child Health Hospital affiliated with Shanghai Jiao Tong University School of Medicine, included women diagnosed with uterine niche.

NCT Number	NCT07279181
Lead Sponsor	International Peace Maternity and Child Health Hospital
Conditions	Uterine Niche
Enrollment	60 participants
Start Date	2024-06-01
Primary Completion	2025-02-28 (estimated)
Study Completion	2025-02-28 (estimated)
Updated on ClinicalTrials.gov	2026-01-21