Clinical Trial

Decision Support Tool to Integrate PrEP Into Emergency Departments

Not Yet Recruiting Phase 1
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Summary
This project will explore the development of a personalized decision support tool to assist with pre-exposure prophylaxis (PrEP) initiation and persistence among patients identified in the emergency department (ED) and urgent care settings as PrEP eligible. First, the investigators will use a sequence of validated implementation science methodologies to develop and validate a decision support tool designed to optimize PrEP persistence by strengthening self-efficacy by addressing the multifaceted medical and social needs of the individual patient. The investigators will then test the preliminary effectiveness of this tool through a pilot stepped wedge implementation trial in two EDs and an urgent care in Baltimore, MD and Washington, DC among 120 PrEP eligible patients to determine PrEP initiation, linkage to care, persistence, and adherence rates.
Trial Details
NCT Number NCT07279129
Lead Sponsor George Washington University
Collaborators: National Institute of Mental Health (NIMH), Johns Hopkins University
Conditions HIV
Enrollment 120 participants
Start Date 2027-01-15
Primary Completion 2028-04-15 (estimated)
Study Completion 2028-09-09 (estimated)
Updated on ClinicalTrials.gov 2025-12-12