Clinical Trial

Applause Study I - Append System Early Feasibility Study

Name: Applause Study I - Append System Early Feasibility Study — clinical trial record (NCT07278869)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: Applause

Recruiting

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Summary

This early feasibility study is intended to evaluate the safety and feasibility of the Append System for eliminating the left atrial appendage (LAA) through a transcatheter procedure that invaginates and ligates the LAA tissue.

Protocol Amendment History 1 change

minor Completion pushed: 2031-12 -> 2033-03 2026-05-28

Trial Details

NCT Number	NCT07278869
Lead Sponsor	Append Medical Ltd.
Conditions	Non Valvular Atrial Fibrillation
Enrollment	15 participants
Start Date	2026-04-29
Primary Completion	2027-09 (estimated)
Study Completion	2033-03 (estimated)
Updated on ClinicalTrials.gov	2026-05-27