Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis

In the context of this randomized controlled study, patients who are diagnosed with Rheumatoid arthritis in Cerrahpaşa Faculty of Medicine Hospital, will be taken into a rehabilitation program by a qualified physiotherapist to improve their pain, pain perception, inflammatory markers and quality of life, with one of the pain neuroscience education, vagal nerve stimulation and traditional exercise interventions. The results of each intervention method will be analyzed and compared at the end of the 8 weeks study protocol.

NCT Number	NCT07274124
Lead Sponsor	Medipol University Collaborators: Istanbul University - Cerrahpasa
Conditions	Rheumatic Diseases, Rheumatoid Arthritis (RA)
Enrollment	36 participants
Start Date	2026-01
Primary Completion	2027-05 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2025-12-10