Clinical Trial

Effect of H. Pylori Eradication on The Improvement of Gastrointestinal Symptoms

Study acronym: HPE-GI
Not Yet Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated December 16, 2025 (before its estimated June 20, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to evaluate the effect of Helicobacter pylori eradication on gastrointestinal symptoms in adult patients. H. pylori infection is a common cause of dyspepsia and other upper gastrointestinal complaints. The trial will assess whether successful eradication therapy leads to significant improvement in symptoms compared to baseline. Adult patients diagnosed with H. pylori infection will receive standard eradication treatment, and symptom changes will be monitored using validated questionnaires over a defined follow-up period.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-11-26.
Trial Details
NCT Number NCT07272681
Lead Sponsor Amany Usama Ahmed Arafa
Conditions Helicobacter Pylori Infection, Dyspepsia, Gastrointestinal Symptoms
Enrollment 100 participants
Start Date 2025-12-20
Primary Completion 2026-06-20 (estimated)
Study Completion 2026-12-20 (estimated)
Updated on ClinicalTrials.gov 2025-12-16