Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia

The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby. The study focuses on adults who give birth at term and choose to receive an epidural for pain relief. The main questions the study aims to answer are: How often does maternal blood pressure fall within 30 minutes after the epidural? When blood pressure falls, how often do participants need treatments such as fluids or medicines that raise blood pressure? Do changes in the baby's heart rate happen during this time, and do they need treatment? Are certain parent or labor factors linked to a higher chance of blood pressure drops? How often does an urgent cesarean delivery happen because of maternal low blood pressure or concerning fetal heart rate changes soon after the epidural? Participants will not be asked to do anything different from usual care. Researchers will: Review routine vital signs recorded before and after the epidural Review treatments given, such as IV fluids or blood-pressure-raising medicines Review the baby's heart-rate monitoring Record delivery information, including whether an urgent cesarean was needed This study does not change clinical care in any way. It uses information already collected during standard labor and delivery.

NCT Number	NCT07272018
Lead Sponsor	The Chaim Sheba Medical Center
Conditions	Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
Enrollment	480 participants
Start Date	2025-12
Primary Completion	2026-02 (estimated)
Study Completion	2026-03 (estimated)
Updated on ClinicalTrials.gov	2025-12-09