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Effect of Total Intravenous Anesthesia vs Inhalational Anesthesia on the Level of Inflammatory Markers

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 5 months later Aug 2026 → Feb 2027
See other at-risk trials from Ain Shams University

Record History

  1. Primary completion pushed from Aug 2026 to Feb 2027 Completion pushed from Oct 2026 to Oct 2027 · Eligibility criteria expanded, about 15 words · Secondary endpoints: details revised at 3 of 4 entries · 1 more Show 4 more changesShow less
    • Completion pushed from Oct 2026 to Oct 2027
    • Eligibility criteria expanded, about 15 words
    • Secondary endpoints: details revised at 3 of 4 entries
    • Study description revised
  2. Trial status changed: Not Yet Recruiting → Active, Not Recruiting Start date changed from estimate of Feb 2026 to Feb 1, 2026 · Site contact updatedv4 Show 2 more changesShow less
    • Start date changed from estimate of Feb 2026 to Feb 1, 2026
    • Site contact updated
  3. Start date: Dec 2025 to Feb 2026 Primary completion date: Apr 2026 to Aug 2026v3 Show 1 more changeShow less
    • Primary completion date: Apr 2026 to Aug 2026
  4. Study description shortened, about 397 wordsv2 See this version in full on ClinicalTrials.gov ↗
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study aims to compare the effects of total intravenous anesthesia (TIVA) vs inhalational anesthesia on postoperative levels of inflammatory markers, length of hospital stay, and the incidence of postoperative nausea and vomiting in patients undergoing inguinal hernia repair. Number participants: Participants will be divided into 2 groups with sample size of at least 20 patients per group. Plan of the work: All patients will receive general anesthesia according to Ain Shams hospital protocol which follows the standards of the American Society of Anesthesiologists. Group A will be TIVA group and Group B will be Sevoflurane group. Sample Collection and Laboratory Analysis: Venous blood samples will be collected from each patient at three time points: preoperative (baseline, sample 0), 6 hours postoperative (sample 1), and 24 hours postoperative (sample 2).
Trial Details
NCT Number NCT07271459
Lead Sponsor Ain Shams University
Conditions Anesthesia
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov