The Effect of Collagen In Tooth Extraction Procedures

This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the study. Patients will be divided into two comparable groups in a randomized manner. The first group will proceed with tooth extraction only, which will be left for spontaneous healing. The second (test) group will receive an additional collagen matrix graft after the extraction, which will be sutured to the tooth socket. Sutures will be removed 1 week after surgery. Both groups will undergo CBCT imaging on the day of surgery and at the 3-month follow-up. Differences in bone measurements like height and width will be recorded as well as soft tissue measurements like thickness and width. Data acquired from two groups will be compared against each other to specify the protective effect of the applied collagen matrix graft.

NCT Number	NCT07270510
Lead Sponsor	Altinbas University
Conditions	Extraction Socket Healing, Extraction, Tooth
Enrollment	24 participants
Start Date	2025-07-01
Primary Completion	2026-01-01 (estimated)
Study Completion	2026-02-20 (estimated)
Updated on ClinicalTrials.gov	2025-12-08