A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function

The purpose of this study is to understand the effects of decreased liver function on the study medicine (PF-07328948). People with decreased liver function may process the study medicine differently from healthy people. Study is seeking participants who: * Are between 18 and 75 years of age. * Have a BMI (body mass index) of 17.5 to 40 kg/m2, inclusive, and a total body weight of more than or equal to 45 kilograms or 99 pounds. Participants will take the study medicine as a tablet once at the study clinic and then will stay onsite for about 6 days. During this time, the study team will check for the participant's treatment experience and take some blood samples to test the level of PF-07328948. This will help understand if certain level of decreased liver function could affect the study medicine being processed in the body.

NCT Number	NCT07269301
Lead Sponsor	Pfizer
Conditions	Hepatic Impairment, Healthy
Enrollment	26 participants
Start Date	2025-12-22
Primary Completion	2027-02-23 (estimated)
Study Completion	2027-02-23 (estimated)
Updated on ClinicalTrials.gov	2026-07-23