Clinical Trial

Long-Term Study of CartiPRO for Knee Pain Due to Osteoarthritis or Cartilage Damage

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated January 20, 2026 (before its estimated February 2026 completion). Its status may not reflect the trial's current state.
Summary
This clinical trial aims to evaluate and compare the efficacy and safety of CartiPRO, an approved intra-articular atelocollagen injection, versus Synovian injection for the relief of knee pain in patients with knee osteoarthritis. The investigational device is administered intra-articularly, with a second injection given 24 weeks after the first dose. Primary and secondary endpoints include changes in pain scores (VAS), functional assessments (WOMAC, SF-36), and safety evaluations over a 36-week period.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-11-24; most recent amendment 2026-01-15.
Trial Details
NCT Number NCT07267793
Lead Sponsor DALIM TISSEN Co., Ltd.
Conditions Osteoarthritis, Knee Pain Arthritis, Cartilage Defects of the Knee, Knee Osteoarthritis, Degenerative Joint Disease of Knee
Enrollment 194 participants
Start Date 2025-07-03
Primary Completion 2026-02 (estimated)
Study Completion 2026-10 (estimated)
Updated on ClinicalTrials.gov 2026-01-20