Using Virtual Reality Technology on Depression, Anxiety, and Stress Among Palestinian Patients Undergoing Breast Biopsy

The goal of this randomized controlled trial was to investigate the impact of Virtual Reality (VR) technology on depression, anxiety, and stress levels among Palestinian patients undergoing breast biopsy. The study aimed to evaluate the effectiveness of VR as a non-pharmacological intervention to reduce psychological distress associated with the biopsy procedure. The main research hypotheses are: H01: There will be no significant difference in depression levels between patients who receive immersive VR during breast biopsy and those who receive standard care. H02: There will be no significant difference in anxiety levels between patients who receive immersive VR during breast biopsy and those who receive standard care. H03: There will be no significant difference in stress levels between patients who receive immersive VR during breast biopsy and those who receive standard care. Participants will: Receive either a VR intervention or standard care during their breast biopsy. Wear a VR headset for 15-30 minutes, experiencing a calming virtual environment designed to promote relaxation. Complete assessments of depression, anxiety, and stress before and after the procedure using validated psychological questionnaires.

NCT Number	NCT07267741
Lead Sponsor	Nablus University for Vocational and Technical Education
Conditions	Depression, Anxiety, Stress
Enrollment	80 participants
Start Date	2025-12-10
Primary Completion	2026-01-10 (estimated)
Study Completion	2026-02-10 (estimated)
Updated on ClinicalTrials.gov	2025-12-05