Clinical Trial

Investigating MPXV Viral Clearance in Mpox Cases and Secondary Attack Rate in Contacts

Study acronym: MOVIE-TRACE
Completed
View on ClinicalTrials.gov →
Summary
The MOVIE-TRACE project includes two complementary observational studies designed to improve the understanding of Mpox virus infection and its transmission within affected communities. The MOVIE study aims to describe the dynamics of viral clearance in patients with confirmed Mpox. It measures how the viral load changes over time in different biological samples to inform decisions about patient management and isolation guidelines. The TRACE study focuses on understanding how mpox spreads from confirmed cases to their contacts. It will estimate the Secondary Attack Rate (SAR) and identify factors associated with transmission risk. The results will help guide public health strategies for contact tracing, vaccination, and outbreak control.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-11-24.
Status change: Recruiting → Completed 2026-04-27
Trial Details
NCT Number NCT07267390
Lead Sponsor Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Collaborators: University of Kinshasa, London School of Hygiene and Tropical Medicine
Conditions Mpox (Monkeypox)
Enrollment 550 participants
Start Date 2025-10-31
Primary Completion 2026-02-27 (estimated)
Study Completion 2026-02-27 (estimated)
Updated on ClinicalTrials.gov 2026-05-01