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Acute Effects of Transcutaneous Electrical Nerve Stimulation at Acupoints on Nociceptive Transmission

StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated July 8, 2026 (before its estimated July 15, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Jul 2026 to Jul 15, 2026v2 Show 4 more changesShow less
    • Study completion date: Jul 2026 to Jul 31, 2026
    • Start date: Nov 25, 2025 to Sep 5, 2025
    • Eligibility criteria shortened, about 32 words
    • Study title shortened, about 7 words
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation (TENS) applied to acupoints can modulate pain transmission and cortical processing in healthy adult volunteers. The main questions it aims to answer are: * Does TENS at Zhongzhu (SJ3) and Hegu (LI4) change pain-related evoked potentials (PREPs)? * Does acupoint electrical stimulation alter nociceptive pathways reflected by PREP waveform modulation? Researchers will compare PREPs recorded before and after TENS at the two acupoints to see if TENS produces measurable effects on cortical nociceptive responses. Participants will receive low-frequency TENS applied to Zhongzhu (SJ3) and Hegu (LI4), and undergo PREP assessments before and after the intervention to measure cortical responses to standardized noxious stimuli.
Trial Details
NCT Number NCT07267052
Lead Sponsor China Medical University Hospital
Conditions
(from sponsor)		 Pain Management
Related terms Agnosia
Enrollment 35 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov