Clinical Trial

SUCCESS Score Validation in Fuchs Dystrophy

Study acronym: SUCCESS
Recruiting
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Record status
This record was last updated December 4, 2025 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
This prospective multicenter diagnostic study aims to externally validate and extend the SUCCESS Score for predicting the need for endothelial keratoplasty after cataract surgery in patients with Fuchs endothelial corneal dystrophy (FECD). The model's performance and clinical utility are assessed using discrimination, calibration, and reclassification metrics.
Trial Details
NCT Number NCT07265388
Lead Sponsor Instituto Ramón y Cajal de Investigación Sanitaria
Conditions Fuchs Endothelial Corneal Dystrophy
Enrollment 250 participants
Start Date 2020-06-01
Primary Completion 2026-07 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-12-04