Clinical Trial

Integrative Epidemiology of Prognosis in Patients With Acute Alcoholic Hepatitis at AP-HP

Study acronym: DIONYSOS
Recruiting
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Summary
Acute alcoholic hepatitis (AAH) is a severe liver disease that often occurs in individuals with prolonged excessive alcohol consumption. Patients face a high risk of liver failure, complications, and death, despite available treatments. Current prognostic scores based on blood tests provide limited accuracy and do not capture the full complexity of the disease. The purpose of this study is to improve the prediction of patient outcomes after a diagnosis of acute alcoholic hepatitis. By integrating clinical, biological, and histological information collected from the AP-HP data warehouse, the investigators aim to identify more reliable prognostic markers. This could help physicians better tailor treatments and improve survival of patients affected by this condition.
Trial Details
NCT Number NCT07262515
Lead Sponsor Assistance Publique - Hôpitaux de Paris
Collaborators: URC-CIC Paris Descartes Necker Cochin, Ministry of Health, France
Conditions Acute Alcoholic Hepatitis
Enrollment 1,400 participants
Start Date 2024-07-19
Primary Completion 2025-12 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2025-12-03