Clinical Trial

Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy

Not Yet Recruiting
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Record status
This record was last updated December 3, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery. They can also worsen low blood pressure in patients with unstable circulation. Because of these risks, multimodal analgesia is recommended to reduce opioid use. Research on other non-opioid options is limited. Systemic lidocaine offers anti-inflammatory and opioid-sparing benefits and improves recovery in elective colorectal surgery, but its role in emergency laparotomy is still unclear and requires further study.
Trial Details
NCT Number NCT07262242
Lead Sponsor Cairo University
Conditions Emergency Abdominal Surgery, Opioid Sparing Anaesthesia
Enrollment 120 participants
Start Date 2025-12
Primary Completion 2026-04 (estimated)
Study Completion 2026-04 (estimated)
Updated on ClinicalTrials.gov 2025-12-03