Clinical Trial

Recovery Rate From Category II to Category I EFM Tracings in Pregnant Women Receiving Bolus vs Continuous Intravenous Fluid Administration

Study acronym: IUR-RCT
Completed
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Summary
The goal of this clinical trial is to learn which method of intravenous fluid works better for treating abnormal fetal heart rate patterns during labour in low-risk pregnant women at term. The main question it aims to answer is: Does a rapid fluid bolus (500 mL given quickly) convert abnormal fetal heart rate tracings to normal within 30 minutes better than slow continuous infusion? Researchers will compare a 500 mL normal saline bolus followed by continuous infusion to continuous infusion alone to see which method improves fetal heart rate patterns faster. Participants will: * Be placed in the left lateral position and receive supplemental oxygen by face mask * Have oxytocin stopped if it is being given * Receive normal saline through an IV line - either as a rapid bolus or a slow continuous drip, depending on which group they are assigned to * Have fetal heart rate monitored continuously and assessed at 30, 60, and 120 minutes * Have blood pressure, heart rate, and oxygen levels checked every 15 minutes * Have two ultrasound measurements taken - one of a vein in the abdomen and one of blood flow in the umbilical cord - at the start and at 30 minutes
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-11-20.
Status change: Recruiting → Completed 2026-06-07
Trial Details
NCT Number NCT07260240
Lead Sponsor Queen Savang Vadhana Memorial Hospital, Thailand
Conditions Fetal Non Reassuring
Enrollment 60 participants
Start Date 2025-12-10
Primary Completion 2026-03-27 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-10