Generation of Endometrial Carcinoma Organoids

A prospective pilot genetic study to evaluate the feasibility of generating organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice. Samples will be collected from collaborating extramural facilities, with the aim of analyzing the impact of transport on tissue viability and the success of organoid culture. This study is for exploratory purposes only, without altering the diagnostic and therapeutic pathways of the participants.

NCT Number	NCT07258186
Lead Sponsor	Regina Elena Cancer Institute Collaborators: Azienda Ospedaliera Universitaria Integrata Verona
Conditions	Endometrial Cancer
Enrollment	20 participants
Start Date	2025-03-23
Primary Completion	2028-09-23 (estimated)
Study Completion	2028-09-23 (estimated)
Updated on ClinicalTrials.gov	2025-12-02