Minimally Invasive Radical Hysterectomy Using Endoscopic Stapler in Stage IB2 or IIA1 Cervical Cancer

This study is a multicenter, open-label, non-inferiority, randomized controlled, investigator-initiated clinical trial comparing the efficacy and safety of open radical hysterectomy versus minimally invasive radical hysterectomy using an endoscopic stapler as surgical treatments for early cervical cancer.

NCT Number	NCT07256977
Lead Sponsor	Seoul National University Hospital Collaborators: Ajou University School of Medicine, SMG-SNU Boramae Medical Center, Konkuk University, DongGuk University, Keimyung University, National Cancer Center, Korea, The Catholic University of Korea, Wonju Severance Christian Hospital, Kangbuk Samsung Hospital, Asan Medical Center, Samsung Medical Center, Sinchon Severance Hospital, Yonsei University College of Medicine
Conditions	Cervical Cancer Stage IB2, Cervical Cancer Stage IIa
Enrollment	494 participants
Start Date	2026-01-01
Primary Completion	2034-12-31 (estimated)
Study Completion	2035-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-12-02