Clinical Trial

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Cognitive Performance and Sex Differences

Not Yet Recruiting

Record status

This record was last updated December 1, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.

Summary

This study investigates the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on cognitive performance in healthy adults. The study uses a sham-controlled, cross-over design in which each participant receives both active taVNS and sham stimulation in separate sessions. Each participant completes both conditions (active and sham) in a randomized order using a crossover design. Cognitive performance will be assessed before and after each session using standardized tests. The study also explores whether males and females respond differently to taVNS, in order to identify potential sex-related differences in cognitive outcomes.

Trial Details

NCT Number	NCT07256080
Lead Sponsor	Bahçeşehir University
Conditions	Cognitive Assessment, Cognition, taVNS, Vagus Nerve Stimulation, Executive Functions, Healthy Participants, Neuromodulation, Sex Differences
Enrollment	60 participants
Start Date	2025-12
Primary Completion	2026-04 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2025-12-01