Clinical Trial

Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes

Study acronym: O3RETINA
Completed
View on ClinicalTrials.gov →
Summary
This double-blind, placebo-controlled randomized clinical trial evaluates the effects of omega-3 fatty acid supplementation on retinal vascular structure and function in children and adolescents with type 1 diabetes. The study compares omega-3 supplementation with placebo to assess changes in retinal microvascular parameters, retinal blood flow, visual function, and systemic biomarkers over time, as well as the safety and tolerability of supplementation during the study period.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-11-19; most recent amendment 2026-06-25.
Status change: Recruiting → Completed 2026-04-27
Trial Details
NCT Number NCT07255326
Lead Sponsor University of Faisalabad
Conditions Diabetic Retinopathy, Type 1 Diabetes, Omega 3 Fatty Acids
Enrollment 70 participants
Start Date 2025-02-12
Primary Completion 2026-01-30 (estimated)
Study Completion 2026-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-30