Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07255157 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Peripheral Helper T-cells in Common Variable ImmunoDeficiency

Study acronym: TAPDI
StatusRecruiting
PhaseNot applicable
Started2026-07-09
View on ClinicalTrials.gov ↗

Amendment history

2026-08-03
Study Identification, Study Status, Contacts/Locations v2
Recruitment opened
Primary completion pushed: 2027-12 → 2028-01
Completion pushed: 2027-12 → 2028-01
Start dateestimated 2025-12→confirmed 2026-07-09
Study sitesdetails revised at 1 of 1 site
2025-12-02
Study Status, Study Description, Eligibility v1
Eligibility criteria+1 characters
[...] ent. Exclusion Criteria: Patients on corticosteroids and/or immnosuppressantsimmunosuppressants; Patients with a primary immunodeficiency genetically chara [...]
Study description+1 characters
[...] or CVID patients with non-infectious complications (CVIDc). OurThe preliminary results show that CVIDc patients have an increa [...] hysiology and which is also expanded in CVIDc patients. The ivestigatorsinvestigators observed that CXCR3+ cells were increased in the spleen of [...] g extra-follicular reaction and then B-cell tolerance loss. OurThe hypothesis is that alterations in T-B cell collaboration le [...]
2025-11-19
Original filing
The aim is to determine whether whether Tph could support non-infectious complications through providing help to pathological B-cells.
Trial Details
NCT Number NCT07255157
Lead Sponsor University Hospital, Bordeaux
Conditions Common Variable Immunodeficiency
Enrollment 60 participants
Start Date 2026-07-09
Primary Completion 2028-01 (estimated)
Study Completion 2028-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-05