Analysis of the Biomechanical Impact of Lower Limb Length Inequality in PEDiatrics

Lower limb length discrepancy (LLD) is a frequent condition in pediatric orthopedics. Even moderate discrepancies can induce pelvic obliquity and compensatory scoliosis, modifying the distribution of joint loads at the hips and lumbar spine. These biomechanical imbalances are suspected to contribute to early degenerative conditions such as osteoarthritis or chronic low back pain. The aim of this study is to quantify the biomechanical impact of LLD in children aged 10 to 15 years, using a combination of low dose biplanar EOS imaging (EOS Imaging System) and synchronized ground reaction force (GRF) measurements from integrated force platforms. These data will be used in musculoskeletal models developed in collaboration with the Biomechanics and Impact Mechanics Laboratory (LBMC, Laboratoire de Biomécanique et Mécanique des Chocs), enabling the estimation of hip joint and lumbar intervertebral disc loads. This is the first pediatric study integrating EOS imaging, force platforms, and personalized musculoskeletal modeling to explore the mechanical consequences of LLD. The findings are expected to improve clinical reasoning and guide early therapeutic strategies.

NCT Number	NCT07254351
Lead Sponsor	Hospices Civils de Lyon
Conditions	Lower Limb Length Discrepancy (LLD) in Children
Enrollment	100 participants
Start Date	2026-04-07
Primary Completion	2029-06-07 (estimated)
Study Completion	2029-06-07 (estimated)
Updated on ClinicalTrials.gov	2026-04-17