Dyadic, App-supported Collaborative Care Intervention Trial for Family Caregivers of People Living With Dementia

In Germany, approximately 1.8 million individuals are living with dementia, representing a considerable share of those requiring long-term care. Many people with dementia (PlwD) express the desire to remain in their home environment for as long as possible. However, the progressive cognitive and physical decline associated with the disease renders caregiving increasingly time-intensive and places a substantial burden on family members. In the absence of sufficient support structures, maintaining home-based care becomes difficult, creating additional strain on the health care system. The study aims to address these challenges through an innovative intervention. Its primary objectives are: (1) to evaluate whether a dyadic care management model, delivered by specialized nurses with expertise in dementia care and supported by a mobile health application that provides direct access to caregiving experts and memory clinics, can help stabilize the home care situation; (2) to determine whether this approach reduces caregiver burden; and (3) to assess its effectiveness in alleviating neuropsychiatric symptoms in PlwD, compared to usual care.

NCT Number	NCT07251088
Lead Sponsor	German Center for Neurodegenerative Diseases (DZNE) Collaborators: University Medical Center Rostock, AGAPLESION ELISABETHENSTIFT gGmbH, AOK - Die Gesundheitskasse für Niedersachsen, Gemeinnützige Gesellschaft für Psychiatrie Reutlingen mbH, Georg-August-Universität Göttingen, IKK gesund plus, Karlsruhe Institute of Technology, Otto-von-Guericke-Universität Magdeburg, Universität Konstanz, Universität zu Köln, University Medicine Greifswald, Federal Joint Committee
Conditions	Dementia, Nurse Care Coordination, Informal Caregiver
Enrollment	554 participants
Start Date	2026-01-01
Primary Completion	2028-06 (estimated)
Study Completion	2028-12 (estimated)
Updated on ClinicalTrials.gov	2025-11-26