Enhanced Prediction Model for Major Adverse Events Following Acute Myocardial Infarction

Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide. Although early revascularization has markedly improved short-term outcomes, the incidence of major adverse cardiovascular events after the index event remains unacceptably high, posing a formidable clinical challenge. Contemporary risk-stratification instruments rely predominantly on a restricted set of conventional clinical variables and therefore fail to capture the full spectrum of individual pathophysiological complexity. To overcome these limitations, the present investigation aims to develop a post-AMI prognostic model that integrates comprehensive multimodal data.

NCT Number	NCT07250152
Lead Sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions	Myocardial Infarction (MI)
Enrollment	1,544 participants
Start Date	2025-12-01
Primary Completion	2027-09-30 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-11-26