Clinical Trial

Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

Completed
View on ClinicalTrials.gov →
Summary
This study compares ketamine/fentanyl versus ketamine/lidocaine in term of their impact on cerebral perfusion during CABG. No prior data address these effects, and the goal is to identify the induction regimen that better preserves cerebral oxygenation.
Protocol Amendment History 2 changes
critical Trial completed 2026-08-08
notable Enrollment increased: 40 -> 48 participants 2026-08-08
Trial Details
NCT Number NCT07248202
Lead Sponsor Cairo University
Conditions Coronary Artery Disease (CAD), Left Ventricular (LV) Systolic Dysfunction, Induction Anesthesia, Coronary Bypass Graft Surgery, Ketamine, Fentanyl, Lidocaine
Enrollment 48 participants
Start Date 2025-12-01
Primary Completion 2026-06-25 (estimated)
Study Completion 2026-07-25 (estimated)
Updated on ClinicalTrials.gov 2026-08-07