Heart Failure Management for Patient With CIED Remotely Monitored

This randomized, controlled, open-label, parallel, multicenter clinical study evaluates the efficacy of SmartSignalHF compared with heart failure (HF) remote monitoring (RM) standard of care in implanted patients with heart failure. The primary objective is to determine whether SmartSignalHF reduces all-cause mortality and HF hospitalizations at 12 months.

NCT Number	NCT07247032
Lead Sponsor	Implicity
Conditions	Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Decompensation, CRT and/or ICD
Enrollment	1,132 participants
Start Date	2025-12-19
Primary Completion	2027-05 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-03-31