Multicentre Study on the Impact of Transmucosal Abutment Surface Characteristics on Peri-implant Tissues.

The main objective of the study is to perform proteomic adsorption analysis on machined (grey) and anodised (pink) surfaces and compared them. The aim is to evaluate the regenerative potential involving improvement in the healing of peri-implant soft tissues in patients with dental implants. This surgery is indicated in healthy patients when they lost their teeth. The main question it seeks to answer is: \- In dental abutments, is anodised surface more effective than machined surface in terms of the degree of healing? The study will include patients who need this type of surgery and meet specific clinical criteria. Each patient will have one of the two dental abutments applied as part of the standard surgical procedure. Subsequently, participants will undergo clinical and proteomic follow-up assessments to evaluate the progress and extent of peri-implant tissue healing over a three-months period.

NCT Number	NCT07246499
Lead Sponsor	University of Valencia Collaborators: University of Santiago de Compostela
Conditions	Peri-implant Tissue Healing Assessed by Proteomic Analysis
Enrollment	25 participants
Start Date	2025-11-01
Primary Completion	2026-03-01 (estimated)
Study Completion	2026-06-05 (estimated)
Updated on ClinicalTrials.gov	2026-07-10