Clinical Trial

Evaluation of the Clinical Contribution of Quantitative MRI in Neuro-imaging

Study acronym: NormaBRAIN
Not Yet Recruiting
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Summary
This study aims to develop the use of a quantitative MRI (qMRI) approach in neuroimaging for MS patients. To achieve this task the main goals of this study will be: * to standardize and optimize qMRI protocols (acquisition time, sensitivity) * to acquire ranges of normative values of qMRI parameters as a function of age and sex at high fields (3 Tesla) and ultra-high fields (UHF for ultra-high field, 7 Tesla) * To develop integrated tools for image processing and the generation of normative models of the healthy brain normative values * To assess the clinical feasibility and the multicenter validation of the multiparametric tools proposed in the case of application to MS.
Trial Details
NCT Number NCT07245589
Lead Sponsor Assistance Publique Hopitaux De Marseille
Conditions Multiple Sclerosis
Enrollment 272 participants
Start Date 2025-12-01
Primary Completion 2028-04-30 (estimated)
Study Completion 2029-11-30 (estimated)
Updated on ClinicalTrials.gov 2025-11-24