Strategies for Proactive Health in People With Kidney Function Decline

This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression. About 1,800 adults with reduced kidney function but not on dialysis will be followed over time at Huashan Hospital, Fudan University. The study will collect information on nutrition, heart and bone health, cognition, and daily functioning through hospital records and a patient mobile app. The goal is to understand the links between nutrition, metabolism, and organ function, and to develop integrated strategies for early prevention and management of chronic kidney disease.

NCT Number	NCT07245186
Lead Sponsor	Huashan Hospital Collaborators: Jingan District Central Hospital of Shanghai (Jingan Branch of Huashan Hospital Affiliated to Fudan University), Shanghai Changfeng community Healthcare center, Putuo, Shanghai, China
Conditions	Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty, Cognitive Dysfunction, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
Enrollment	1,800 participants
Start Date	2021-01-01
Primary Completion	2029-12-30 (estimated)
Study Completion	2029-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-11-24