Clinical Trial

REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention

Study acronym: REDO-AF
Not Yet Recruiting
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Summary
The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.
Trial Details
NCT Number NCT07245147
Lead Sponsor Jacqueline Joza
Conditions Atrial Fibrillation (AF), AV Node Ablation, Left Bundle Branch Pacing
Enrollment 16 participants
Start Date 2025-11
Primary Completion 2026-12 (estimated)
Study Completion 2027-09 (estimated)
Updated on ClinicalTrials.gov 2025-11-24