Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy

The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are: Does ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more? Does seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy? Researchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them. Participants will: Follow specific instructions to either ejaculate or abstain before surgery Undergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery Have their surgical dissection time and difficulty rated by the operating surgeon

NCT Number	NCT07243795
Lead Sponsor	National Taiwan University Hospital
Conditions	Prostate Cancer Patients Undergoing Radical Prostatectomy
Enrollment	40 participants
Start Date	2025-12-01
Primary Completion	2026-08-01 (estimated)
Study Completion	2026-10-09 (estimated)
Updated on ClinicalTrials.gov	2025-12-03