Clinical Trial

SYSTANE® PRO vs. MIEBO™ in Dry Eye Disease

Completed Phase 4
View on ClinicalTrials.gov →
Summary
This is a prospective, randomized, double-masked, multi-site clinical trial designed to compare the efficacy of SYSTANE® PRO (Alcon Laboratories, Inc.) to MIEBO™ (Bausch + Lomb) in treating symptoms of evaporative dry eye disease (DED). The primary goal is to determine whether SYSTANE® PRO is non-inferior to MIEBO™ after one month of treatment, based on change in Ocular Surface Disease Index (OSDI) scores.
Protocol Amendment History 3 changes
critical Trial completed 2026-08-07
notable Primary completion moved earlier: 2026-09-30 -> 2026-07-28 2026-08-07
minor Completion moved earlier: 2026-09-30 -> 2026-07-28 2026-08-07
Trial Details
NCT Number NCT07243275
Lead Sponsor Indiana University
Collaborators: Alcon Research
Conditions Dry Eye Disease (DED)
Enrollment 269 participants
Start Date 2026-02-18
Primary Completion 2026-07-28 (estimated)
Study Completion 2026-07-28 (estimated)
Updated on ClinicalTrials.gov 2026-08-06