Sugammadex and Menstrual Cycle in Postoperative Nausea and Vomiting

This observational study aims to evaluate the relationship between menstrual cycle phases and the incidence of postoperative nausea and vomiting (PONV) in women of reproductive age undergoing septorhinoplasty surgery. The study's primary objective is to determine whether different phases of the menstrual cycle are associated with variations in PONV frequency. As a secondary objective, the relationship between menstrual phases, PONV incidence, and the use of sugammadex during anesthesia will be analyzed. No additional intervention will be applied beyond routine clinical practice; all data will be collected prospectively from anesthesia records and postoperative evaluations.

NCT Number	NCT07242209
Lead Sponsor	Sakarya University
Conditions	Postoperative Nausea and Vomiting, Menstrual Cycle
Enrollment	60 participants
Start Date	2025-12-18
Primary Completion	2026-03-09 (estimated)
Study Completion	2026-05-15 (estimated)
Updated on ClinicalTrials.gov	2026-07-07