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Mesenchymal Stem Cells for Chronic Kidney Diseases

StatusNot Yet Recruiting
PhasePhase 1/2
Started
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Record History

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  1. Start date: Nov 15, 2025 to Jan 1, 2026
    • Interventions: The experimental group will receive an intravenous injection of allogeneic MSCs.The control group will receive a placebo, which is an… to 0.9% sodium chloride (Drug), MSCs (Drug)
    • Eligibility criteria shortened, about 17 words
    • Study title shortened, about 4 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will evaluate the effect of intravenous injection of umbilical cord tissue derived mesenchymal stem cells (UMSCs) on the improvement of renal function in patients with chronic kidney disease (CKD) at stage 3 or 4, with the change of estimated glomerular filtration rate (eGFR) as the primary endpoint, and other changes in renal function laboratory indicators, changes in other organ system function laboratory indicators, and adverse reaction events as secondary endpoints. This trial aims to further evaluate the efficacy and safety of UMCSs in CKD patients, and provide new insights into expanding the clinical treatment strategies, delaying the progression and improving the prognosis of CKD patients.
Trial Details
NCT Number NCT07240987
Lead Sponsor The First Affiliated Hospital of Air Force Medicial University
Conditions
(from sponsor)		 Kidney Disease, Chronic, Diabetic Kidney Disease (DKD), Hypertensive Nephropathy
Related terms Diabetic Nephropathies, Hypertensive Nephropathy, Renal Insufficiency, Chronic
Enrollment 32 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov