Xylitol Gum for Promoting Smoking Cessation

The goal of this clinical trial is to learn if 4-week xylitol gum intervention works to promote smoking cessation in daily smokers. It will also learn about the feasibility and acceptability of using xylitol gum. The main questions it aims to answer are: （1）Does xylitol gum help to reduce cigarette consumption and promote smoking cessation? Researchers will compare 4-week xylitol gum intervention to the brief advice to see if xylitol gum works to promote smoking cessation. Participants in the intervention group will receive a 3-month behavioral intervention comprising a 4-week xylitol gum aligned with 12 weeks of instant reminder message support.

NCT Number	NCT07240545
Lead Sponsor	The University of Hong Kong
Conditions	Smoking Cessation, Health Promotion
Enrollment	134 participants
Start Date	2025-11-24
Primary Completion	2026-02-28 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2025-11-21