Influence of Maintaining Apical Patency on Post-Endodontic Pain in Molars

This randomized controlled trial will investigate if maintaining apical patency-a technique where a small file is gently moved past the root's end during cleaning-affects pain after a root canal. The study will include 48 adult patients needing root canal treatment on a back molar tooth with a dead nerve and infection at the root tip. Participants will be randomly assigned to one of two groups: one where the apical patency technique is used, and one where it is not. All other treatment steps will be identical. Patients will record their pain levels on a standard scale (0-100 mm Visual Analog Scale) at 6, 12, 24, 48, and 72 hours after the procedure. The goal is to determine if this specific technique influences the intensity and duration of post-treatment pain

NCT Number	NCT07239752
Lead Sponsor	College of Physicians and Surgeons Pakistan
Conditions	Periapical Periodontitis, Dental Pulp Necrosis
Enrollment	48 participants
Start Date	2026-02-10
Primary Completion	2026-05-10 (estimated)
Study Completion	2026-10-10 (estimated)
Updated on ClinicalTrials.gov	2025-11-20